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The blinded, placebo-controlled randomized clinical trial aims to enroll more than 500 adults who are currently hospitalized with COVID-19 or in an emergency department with anticipated hospitalization…reports Asian Lite News

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Coronavirus protective equipment

A clinical trial to evaluate the safety and effectiveness of hydroxychloroquine, an antimalarial drug, for the treatment of adults hospitalized with COVID-19 has begun in the United States, according to a release of the National Institutes of Health (NIH) on Thursday.

The first participants have enrolled in the trial at Vanderbilt University Medical Center, Tennessee, reported Xinhua news agency.

The blinded, placebo-controlled randomized clinical trial aims to enroll more than 500 adults who are currently hospitalized with COVID-19 or in an emergency department with anticipated hospitalization.

All participants in the study will continue to receive clinical care as indicated for their condition. Those randomized to the experimental intervention will also receive hydroxychloroquine, according to the NIH.

“Effective therapies for COVID-19 are urgently needed,” said James Kiley, director of the Division of Lung Diseases of the National Heart, Lung, and Blood Institute, part of the NIH.

“Hydroxychloroquine has showed promise in a lab setting against SARS-CoV-2, the virus that causes COVID-19 and preliminary reports suggest potential efficacy in small studies with patients. However, we really need clinical trial data to determine whether hydroxychloroquine is effective and safe in treating COVID-19,” he said.

US President Donald Trump and Vice President Mike Pence

While COVID-19 usually presents as an acute respiratory infectious illness, it can damage multiple organ systems, including heart, lung, and blood.

Currently, no therapies have been demonstrated to prevent the progression of COVID-19 to severe illness, but several medicines available in the United States have been proposed as potential therapies, said the NIH.

Hydroxychloroquine is used to treat malaria and rheumatoid conditions such as arthritis. In various studies, the drug has demonstrated antiviral activity, an ability to modify the activity of the immune system, said the NIH.

The drug has an established safety profile at appropriate doses, leading to the hypothesis that it may also be useful in the treatment of COVID-19, according to the NIH.

2 mn tests

US President Donald Trump said there have been more than 2 million coronavirus tests conducted in the US.

“I’m reporting today that we passed 2 million tests completed in the United States,” Trump said during the White House press briefing, adding that the tests are “highly sophisticated and highly accurate”, CNN reported.

US President Donald Trump, from left, Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases; Anne Schuchat, Principal Deputy Director of the Centres for Disease Control, and Human Services Secretary Alex Azar at a White House news conference on Wednesday, Feb. 26, 2020, to discuss the threat of coronavirus. (Photo: White House) by .
US President Donald Trump, from left, Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases; Anne Schuchat, Principal Deputy Director of the Centres for Disease Control, and Human Services Secretary Alex Azar at a White House news conference. (Photo: White House)

Earlier in the briefing, the President said, “Other countries are looking to what we are doing, and our testing operation has now become, far and away, the most sophisticated and the best anywhere.”

However, Trump conceded there will not be mass coronavirus testing for all Americans as the country goes back to work, but also claimed it was not needed.

“We want to have it and we’re going to see if we have it. Do you need it? No. Is it a nice thing to do? Yes. We’re talking about 325 million people and that’s not gonna happen, as you can imagine, and it would never happen with anyone else, either. Other countries do it but they do it in a limited form. We’ll probably be the leader of the pack,” Trump said.

Trump also suggested there would be “massive testing” in “certain areas” of the country.

Also Read – Corona Global Death Toll Exceeds 90,000

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