The trial of Shrien Dewani, 34, will begin at South Africa’s Western Cape High Court. He was extradited from Britain in April and was held at Valkenberg Hospital in Cape Town to ascertain whether he was mentally fit to stand trial.
Dewani has pleaded not guilty to the murder charges.
Dewani and his wife Anni were held at gunpoint while being driven in a taxi through Gugulethu township near Cape Town in November 2010.
Dewani was thrown out of the car later that night and the body of Anni Dewani was found the next day with a single gun shot wound on her neck.
Three men have been convicted in South Africa in the case: Xolile Mngeni, who was found guilty of shooting Anni, taxi driver Zola Tongo, who admitted to his part in the killing, and Mziwamadoda Qwabe, another accused who has also pleaded guilty to Anni’s murder.
Dewani was detained in Britain under the Mental Health Act after being diagnosed with severe depression and post-traumatic stress disorder.