June 13, 2024
2 mins read

Age, Hormones Explain High Autoimmune Rates in Women

Dr Rajeev Gupta, Director – Internal Medicine at the CK Birla Hospital (R), Delhi told IANS that hormonal influence and chromosomal differences are the two main reasons why autoimmune diseases are more common in women…reports Asian Lite News

Age, genetic and hormonal factors may explain why women are disproportionately affected by autoimmune diseases than men, said experts on Wednesday.

Autoimmune disease occurs when the immune system attacks the body’s tissues. Studies show that the condition affects approximately 8 per cent of people worldwide, of which 78 per cent are women.

Dr Rajeev Gupta, Director – Internal Medicine at the CK Birla Hospital (R), Delhi told IANS that hormonal influence and chromosomal differences are the two main reasons why autoimmune diseases are more common in women.

“Women experience significant hormonal fluctuations throughout their lives, particularly during puberty, pregnancy, and menopause. These changes, especially in oestrogen levels, may influence the immune system and make women more susceptible to mistakenly attacking healthy tissues (autoimmunity),” the doctor said.

Regarding chromosomes, women have two X, while men have one X and one Y.

“One theory suggests that the process of inactivating one X chromosome in each female cell might be incomplete sometimes. This could lead to an overabundance of certain genes on the active X chromosome, potentially triggering an overactive immune response and autoimmunity,” Dr Rajeev said.

“Autoimmune disorders in women may be due to the silencing of their second X chromosome by molecules leading to a confusing immune system. This can explain why conditions like multiple sclerosis and lupus are more common in women than men,” added Dr Yathish G C, Lead Consultant – Rheumatology, Aster Whitefield Hospital, Bengaluru.

Commonly, autoimmune diseases become more prevalent after a woman’s thirties, coinciding with hormonal changes associated with ageing.

However, some autoimmune diseases can occur at any age.

“Some like multiple sclerosis usually begin between the ages of 20 and 40 years whereas others such as rheumatoid arthritis start manifesting later in the 40s or early in 50s,” Dr Yathish told.

Dr Harman Singh, Consultant Rheumatologist, Fortis Hospital, Kalyan noted a dramatic rise in autoimmune illnesses, notably among women aged 50 and above.

The experts called for adopting healthy lifestyle practices such as a balanced diet, stopping smoking, avoiding alcohol, stress reduction techniques, being physically fit, and avoiding environmental pollutants.

ALSO READ-Who Should Opt for Hormone Therapy? Expert Insights

Previous Story

Rights Situation Deteriorates in Pak’s Khyber Pakhtunkhwa

Next Story

‘Crew’ Soars with Tabu, Kareena, and Kriti in Heist Comedy

Latest from Health

Generic Drugs Boost Hypertension Control

By setting price ceilings on essential medicines based on average market prices, India successfully kept out-of-pocket costs low while still ensuring manufacturers made sustainable profits India’s focused public health strategies—centered on generic

Millions of vaccines to be made in Oxfordshire

State-of-the-art research centre promises millions of seasonal vaccines, pandemic preparedness, and a boost to Britain’s £100bn life sciences sector…reports Asian Lite News A new era of vaccine innovation has begun in Oxfordshire

Physiotherapy in Healthy Ageing

This year’s theme, “Healthy Ageing – Role of Physiotherapy in Falls and Frailty”, draws attention to the significance of physiotherapy in preventing falls, managing frailty, and supporting dignified ageing among the elderly

Lower BP Target Could Benefit Indians

Beyond salt reduction, experts stressed that controlling hypertension requires a comprehensive approach. Regular exercise, maintaining a healthy body weight, reducing alcohol intake, quitting tobacco, and consuming a balanced diet rich in fruits

Silent Diabetes Crisis Unfolds

The report further highlights that even for those who do receive a diagnosis, the challenges of care and management remain significant A startling number of young adults across the globe are living
Go toTop

Don't Miss

Optimal Nutrition for a Lifetime: Guidelines for Every Age

Consume adequate fibre as it aids digestion and helps maintain