March 28, 2022
1 min read

Scientists develop new combo treatment for head, neck cancer

In traditional clinical treatment, Trametinib has not shown efficiency in inhibiting the targetted hyper-active pathway of cancer cells, said the research…reports Asian Lite News

An Israeli-led research team has developed a potential new treatment for head and neck cancer (HNC), using a targeted drug and immunotherapy, Ben Gurion University (BGU) in southern Israel has announced.

The findings, co-authored by Israeli, Chinese, French, German and US researchers, were published in the Journal for ImmunoTherapy of Cancer on Sunday, Xinhua news agency reported.

Through pre-clinical study, the researchers found a new treatment combination of Trametinib, a cancer drug that brings a type of killer white blood cells to the cancer site, and Anti-PD-1, an immunotherapy that not kills cancer cells directly but blocks a pathway on immune cells to make them more engaged in fighting tumors.

In traditional clinical treatment, Trametinib has not shown efficiency in inhibiting the targetted hyper-active pathway of cancer cells, said the research.

Researchers then analysed tumor-host interaction that facilitates immune escape in tumor-bearing mice, and found that using a short Trametinib treatment can make resistant tumors more sensitive to anti-PD-1 immunotherapy.

“We sincerely hope that oncologists will test this treatment combination in HNC patients, as improving immunotherapy efficacy is crucial for prolonging the survival of cancer patients,” the study’s correspondent author Moshe Elkabets was quoted by the BGU statement as saying.

ALSO READ-Russian scientists barred from Int’l conferences

Previous Story

‘Heropanti 2 is a huge responsibility’

Next Story

3 Days Left For World’s Greatest Show

Latest from Science

UK Space Agency set to clean up space debris

Efforts to clean up space debris mark a pivotal step in the UK’s efforts to protect vital space infrastructure and ensure the long-term safety of the orbital environment The UK Space Agency

UK scientists to synthesise human genome

Five-year SynHG project aims to pave way for next generation of medical therapies and treatment of diseases British researchers have embarked on an ambitious project to construct sections of human genetic material

India Joins Deep-Sea Elite

The Samudrayaan mission aligns with the Indian government’s Blue Economy initiative, which focuses on sustainable use of ocean resources for economic growth…reports Asian Lite News After conquering space with the successful Space

Ax-4 liftoff delayed for safety

The Ax-4 mission is the fourth private astronaut flight to the ISS and the first to include crew members from India, Poland, and Hungary—making it a moment of historic significance for all
Go toTop

Don't Miss

High-Fibre Diet May Delay Rare Blood Cancer

The study enrolled 20 participants with a precancerous blood disorder

Cancer-Preventive Lifestyle Through Dietary Choices

Eat more and more yogurt. In addition to being better equipped